Chirality Control in Enzyme-Catalyzed Dynamic Kinetic Resolution of 1,3-Oxathiolanes
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چکیده
منابع مشابه
Large-scale ruthenium- and enzyme-catalyzed dynamic kinetic resolution of (rac)-1-phenylethanol
The scale-up of the ruthenium- and enzyme-catalyzed dynamic kinetic resolution (DKR) of (rac)-1-phenylethanol (2) is addressed. The immobilized lipase Candida antarctica lipase B (CALB) was employed for the resolution, which shows high enantioselectivity in the transesterification. The ruthenium catalyst used, (eta 5-C5Ph5)RuCl(CO)2 1, was shown to possess very high reactivity in the "in situ" ...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 2015
ISSN: 0022-3263,1520-6904
DOI: 10.1021/acs.joc.5b01585